Harnessing the regenerative properties of inflammation for myelin health across the lifespan.

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Fundamental Research

We are investigating the cellular and molecular mechanisms by which microglia and other immune cells regulate central nervous system white matter health across the lifespan. We are identifying new roles for microglia in myelin development, homeostasis, and ageing.

Translational Research

We are identifying the roles of microglia and other immune cells in regulating myelin development or regeneration following injury, revealing therapeutic targets and strategies for conditions in which central nervous system white matter health is poor (e.g. perinatal brain injury/ cerebral palsy, multiple sclerosis, and normal ageing/ dementia). We actively collaborate with, and consult for, pharmaceutical industry to support drug development.

Approaches & Innovation

We use a comprehensive approach to our research, combining experimental modelling (in vitro, ex vivo, in vivo), transgenic and pharmacological manipulation, ‘omics (digital spatial profiling, RNA seq, sc-RNAseq, TRAPseq, proteomics), drug screening and nanoparticle delivery, and human neuropathological analysis and cell culture.

Recent news
New lab member

New lab member. We welcome new PhD student Bianca Hill from the Department of Immunology at the University of Toronto….

New review article

New review article. Veronica was pleased to contribute to a review article with Pierre Gressens and Bobbi Fleiss on the…

We know the challenges caregivers face in attending conferences. That's why we're thrilled to launch our Caregiver Travel Grant.
Break barriers, enhance your career, and apply for financial support to make conference participation possible.
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RT @PeterHotez: Here it is in visual form, what happens when you get measles with 20% hospitalized vs the minimal risk of the MMR Vaccine.…

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